Triethylamine → N,N,N-Triethyl-2-hydroxyethan-1-aminium bromide
Reaction equation
[Br:1][CH:2]([OH:4])[CH3:3].[CH2:5]([N:7]([CH2:10][CH3:11])[CH2:8][CH3:9])[CH3:6]>ClCCl>[Br-:1].[OH:4][CH2:2][CH2:3][N+:7]([CH2:10][CH3:11])([CH2:8][CH3:9])[CH2:5][CH3:6]Participants
4
Reactant 2
Product 1
Reagents, catalysts & solvents 1
Procedure
Hydroxyethyltriethylammonium bromide was obtained as follows: ##STR14## Bromoethanol (distilled, 2 g, 16 mmole) and triethylamine (1.62 g, 16 mmole) were heated in dichloromethane (30 ml) at 40° C. for 16 hours. After cooling the precipitate was filtered and dried over phosphorus pentoxide to yield hydroxyethyltriethylammonium bromide as a white powder, 1.47 g, 6.5 mmole, 41% yield.
Workup
- temperatureAfter cooling the precipitate
- filtrationwas filtered
- dry with materialdried over phosphorus pentoxide
Sources & evidence
- ORD record
- ord-ce3fd3ecd882480d8c88a83381d44cb1
- Source dataset
- uspto-grants-1998_02
- Patent number
- US05717047
Reaction notes
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