Imidazole → 1H-Imidazole-1-propanenitrile

HRID 865085

Reaction equation

HRID 865085 reaction equation
Cl[CH2:2][CH2:3][C:4]#[N:5].[NH:6]1[CH:10]=[CH:9][N:8]=[CH:7]1.[H-].[Na+]>>[C:4]([CH2:3][CH2:2][N:6]1[CH:10]=[CH:9][N:8]=[CH:7]1)#[N:5]

Participants

4

Reactant 3

HCID 795ImidazoleHCID 109633-ChloropropionitrileHCID 24758Sodium hydride

Product 1

HCID 5572781H-Imidazole-1-propanenitrile

Procedure

Using 2.35 ml of 3-chloropropionitrile, 2.0 g of imidazole and 1.3 g of sodium hydride (60%), 3.2 g of 1-(2-cyanoethyl)imidazole was obtained by the same manner as the procedure of Reference Example 2.

Sources & evidence

ORD record
ord-f0e8d9b9171f4365ae3ac30d2e9a6387
Source dataset
uspto-grants-1996_10
Patent number
US05565479

Linked notes

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