Hydrogen Peroxide → 4-Benzyloxybenzamide

HRID 866378

Reaction equation

HRID 866378 reaction equation
[C:1]([C:3]1[CH:16]=[CH:15][C:6]([O:7][CH2:8][C:9]2[CH:14]=[CH:13][CH:12]=[CH:11][CH:10]=2)=[CH:5][CH:4]=1)#[N:2].[OH:17]O.[OH-].[Na+]>C(O)C>[NH2:2][C:1]([C:3]1[CH:16]=[CH:15][C:6]([O:7][CH2:8][C:9]2[CH:14]=[CH:13][CH:12]=[CH:11][CH:10]=2)=[CH:5][CH:4]=1)=[O:17]

Participants

5

Reactant 3

HCID 784Hydrogen PeroxideHCID 14798Sodium HydroxideHCID 5613714-Benzyloxybenzonitrile

Product 1

HCID 27264314-Benzyloxybenzamide

Reagents, catalysts & solvents 1

HCID 702EthanolSolvent

Procedure

A mixture of 4-cyanophenoxy phenyl methane (10.45g.; 0.05 mole), 30% hydrogen peroxide (20ml) and 6N NaOH (20ml) and ethanol (30ml) was maintained at 40°-50° for 3 hrs., cooled and neutralised. The product was filtered off and recrystallised from ethanol M.p. 186°-7°.

Workup

  1. temperaturewas maintained at 40°-50° for 3 hrs
  2. temperature, cooled
  3. filtrationThe product was filtered off
  4. customrecrystallised from ethanol M.p. 186°-7°

Sources & evidence

ORD record
ord-0a3b581a07434c519f0fd8d13f28977e
Source dataset
uspto-grants-1978_07
Patent number
US04098816

Linked notes

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