Bromide ion → 3-[6-(2-Cyclopropylethylcarbamoyl)pyridazin-3-ylamino]azetidine-1-carboxylic acid tert-butyl ester

HRID 87627

Reaction equation

HRID 87627 reaction equation
[Br-:39].[C:16](=[O:17])([O:18][C:19]([CH3:20])([CH3:21])[CH3:22])[N:23]1[CH2:24][CH:25]([NH2:27])[CH2:26]1.[CH2:57]1[O:58][CH2:59][CH2:60][O:61][CH2:62]1.[CH3:40][CH2:41][CH2:42][CH2:43][N+:44]([CH2:45][CH2:46][CH2:47][CH3:48])([CH2:49][CH2:50][CH2:51][CH3:52])[CH2:53][CH2:54][CH2:55][CH3:56].[CH:1]1([CH2:4][CH2:5][NH:6][C:7](=[O:8])[c:9]2[n:10][n:11][c:12]([Cl:15])[cH:13][cH:14]2)[CH2:2][CH2:3]1.[N:28]12[CH2:29][CH2:30][CH2:31][N:32]=[C:33]1[CH2:34][CH2:35][CH2:36][CH2:37][CH2:38]2>>[CH:1]1([CH2:4][CH2:5][NH:6][C:7](=[O:8])[c:9]2[n:10][n:11][c:12]([NH:27][CH:25]3[CH2:24][N:23]([C:16](=[O:17])[O:18][C:19]([CH3:20])([CH3:21])[CH3:22])[CH2:26]3)[cH:13][cH:14]2)[CH2:2][CH2:3]1

Participants

7

Reactant 6

HCID 259Bromide ionHCID 16028TetrabutylammoniumHCID 312751,4-DioxaneHCID 811841,8-Diazabicyclo(5.4.0)undec-7-eneHCID 1516507Tert-butyl 3-aminoazetidine-1-carboxylateHCID 655615656-Chloro-N-(2-cyclopropylethyl)pyridazine-3-carboxamide

Product 1

HCID 672049743-[6-(2-Cyclopropylethylcarbamoyl)pyridazin-3-ylamino]azetidine-1-carboxylic acid tert-butyl ester

Sources & evidence

ORD record
ord-98d1d95dfeac4d7aaa6b25d1ed71afb2
Source dataset
Training data from https://doi.org/10.1039/C8SC04228D (2/10)

Linked notes

Loading…