C(S([NH:7][C@H:8]([C:21]1[CH:26]=[CH:25][C:24]([O:27][CH2:28][C:29]([F:32])([F:31])[F:30])=CN=1)[C:9]1[N:10]=[N:11][N:12]([C:14]([CH3:20])([CH3:19])[C:15]([O:17][CH3:18])=[O:16])[CH:13]=1)=O)(C)(C)C.[ClH:33].[CH2:34](OCC)[CH3:35]>CO>[Cl-:33].[CH3:18][O:17][C:15](=[O:16])[C:14]([N:12]1[CH:13]=[C:9]([C@H:8]([C:21]2[CH:26]=[CH:25][C:24]([O:27][CH2:28][C:29]([F:31])([F:30])[F:32])=[CH:35][CH:34]=2)[NH3+:7])[N:10]=[N:11]1)([CH3:19])[CH3:20]To a solution of 0.12 g (0.25 mmol) methyl 2-(4-{(S)-[(tert-butylsulfinyl)amino][5-(2,2,2-trifluoroethoxy)pyridin-2-yl]methyl}-1H-1,2,3-triazol-1-yl)-2-methylpropanoate in 1.0 ml MeOH was added 0.96 mL (1.9 mmol) 2.0M HCl in diethyl ether. After 30 min at room temperature, the reaction mixture was concentrated in vacuo to afford (S)-[1-(2-methoxy-1,1-dimethyl-2-oxoethyl)-1H-1,2,3-triazol-4-yl][4-(2,2,2-trifluoroethoxy)phenyl]methanaminium chloride. ES-MS [M+1]+=374.1.
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