Tetrahydrofuran → 5-(2,3-Difluorophenyl)nona-1,8-dien-5-ol

HRID 87818

Reaction equation

HRID 87818 reaction equation
[Br:1][c:2]1[c:3]([F:9])[c:4]([F:8])[cH:5][cH:6][cH:7]1.[CH2:15]=[CH:16][CH2:17][CH2:18][C:19]([CH2:20][CH2:21][CH:22]=[CH2:23])=[O:24].[CH2:25]1[O:26][CH2:27][CH2:28][CH2:29]1.[CH3:10][CH2:11][CH2:12][CH2:13][Li:14]>>[c:2]1([C:19]([CH2:18][CH2:17][CH:16]=[CH2:15])([CH2:20][CH2:21][CH:22]=[CH2:23])[OH:24])[c:3]([F:9])[c:4]([F:8])[cH:5][cH:6][cH:7]1

Participants

5

Reactant 4

HCID 8028TetrahydrofuranHCID 27332601-Bromo-2,3-difluorobenzeneHCID 11083958Nona-1,8-dien-5-oneHCID 178418339Butyllithium

Product 1

HCID 579114555-(2,3-Difluorophenyl)nona-1,8-dien-5-ol

Sources & evidence

ORD record
ord-f1abd36b1bd7495ab4fbf668818cca2a
Source dataset
Training data from https://doi.org/10.1039/C8SC04228D (2/10)

Linked notes

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