N4-Acetylsulfanilamide → N-[4-(6-chloro-2-ethylamino-pyrimidin-4-ylsulfamoyl)-phenyl]-acetamide

HRID 88119

Reaction equation

HRID 88119 reaction equation
[CH3:27][N:28]1[CH2:29][CH2:30][CH2:31][C:32]1=[O:33].[Cl:1][c:2]1[n:3][c:4]([NH:9][CH2:10][CH3:11])[n:5][c:6]([Cl:8])[cH:7]1.[K:12].[S:13]([NH2:14])(=[O:15])(=[O:16])[c:17]1[cH:18][cH:19][c:20]([NH:23][C:24]([CH3:25])=[O:26])[cH:21][cH:22]1>>[c:2]1([NH:14][S:13](=[O:15])(=[O:16])[c:17]2[cH:18][cH:19][c:20]([NH:23][C:24]([CH3:25])=[O:26])[cH:21][cH:22]2)[n:3][c:4]([NH:9][CH2:10][CH3:11])[n:5][c:6]([Cl:8])[cH:7]1

Participants

5

Reactant 4

HCID 8482N4-AcetylsulfanilamideHCID 13387N-methyl-2-pyrrolidoneHCID 5462222PotassiumHCID 64937354,6-dichloro-N-ethylpyrimidin-2-amine

Product 1

HCID 10809139N-[4-(6-chloro-2-ethylamino-pyrimidin-4-ylsulfamoyl)-phenyl]-acetamide

Sources & evidence

ORD record
ord-9b5fac72e6394667b31008e997aae7f1
Source dataset
Training data from https://doi.org/10.1039/C8SC04228D (2/10)

Linked notes

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