Hydrochloric Acid → 2-Methyl-L-cysteine--hydrogen chloride (1/1)

Reaction equation

[ClH:1].C([S:6][CH2:7][C@@:8]([CH3:13])([C:10]([OH:12])=[O:11])[NH2:9])(C)(C)C>>[ClH:1].[CH3:13][C@@:8]([C:10]([OH:12])=[O:11])([CH2:7][SH:6])[NH2:9]

Participants

Reactant 2

HCID 313Hydrochloric Acid

HCID 16679762HCID 16679762, compound

Product 1

HCID 166797632-Methyl-L-cysteine--hydrogen chloride (1/1)

Procedure

Conc. hydrochloric acid (345.3 g) was added to S-tert-butyl-α-methyl-L-cysteine (38.4 g, 201 mmol) produced by the method in EXAMPLE 11, and the resultant mixture was refluxed for 24 hours to obtain an aqueous solution of α-methyl-L-cysteine hydrochloride.

Workup

customproduced by the method in EXAMPLE 11

Sources & evidence

ORD record: ord-b5c05257f2f846a1b62b34dca3979f34
Source dataset: uspto-grants-2015_03
DOI: 10.6084/m9.figshare.5104873.v1
Patent number: US08993800B2

Reaction notes

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