2-Bromopropane → 4-(1-Isopropyl-2-methyl-1H-imidazol-4-ylethynyl)-2-methyl-pyridine

Reaction equation

[CH3:1][C:2]1[CH:7]=[C:6]([C:8]#[C:9][C:10]2[N:11]=[C:12]([CH3:15])[NH:13][CH:14]=2)[CH:5]=[CH:4][N:3]=1.[CH:16](Br)([CH3:18])[CH3:17]>>[CH:16]([N:13]1[CH:14]=[C:10]([C:9]#[C:8][C:6]2[CH:5]=[CH:4][N:3]=[C:2]([CH3:1])[CH:7]=2)[N:11]=[C:12]1[CH3:15])([CH3:18])[CH3:17]

Participants

Reactant 2

HCID 63582-Bromopropane

HCID 178418884HCID 178418884, compound

Product 1

HCID 112301794-(1-Isopropyl-2-methyl-1H-imidazol-4-ylethynyl)-2-methyl-pyridine

Procedure

The title compound, MS: m/e=240.3 (M+H+), was prepared in accordance with the general method of example 1 from 2-methyl-4-(2-methyl-1H-imidazol-4-ylethynyl)-pyridine and isopropylbromide.

Sources & evidence

ORD record: ord-ffc27ed5e3ac42eca87737c19cad4c2d
Source dataset: uspto-grants-2006_08
DOI: 10.6084/m9.figshare.5104873.v1
Patent number: US07091222B2

Reaction notes

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