2-Bromopropane → 2-Cyclopropyl-4-iodo-1-isopropyl-1H-imidazole

HRID 8876

Reaction equation

[CH:1]1([C:4]2[NH:5][C:6]([I:9])=[CH:7][N:8]=2)[CH2:3][CH2:2]1.[CH:10](Br)([CH3:12])[CH3:11]>>[CH:1]1([C:4]2[N:8]([CH:10]([CH3:12])[CH3:11])[CH:7]=[C:6]([I:9])[N:5]=2)[CH2:3][CH2:2]1

Participants

Reactant 2

HCID 63582-Bromopropane

HCID 219853922-cyclopropyl-5-iodo-1H-imidazole

Product 1

HCID 219853902-Cyclopropyl-4-iodo-1-isopropyl-1H-imidazole

Procedure

The title compound, MS: m/e=277.1 (M+H+), was prepared in accordance with the general method of example 1 from 2-cyclopropyl-5-iodo-1H-imidazole (example C) and isopropylbromide.

Sources & evidence

ORD record: ord-bbb848fc5c3b459aa02401eec47626b9
Source dataset: uspto-grants-2006_08
DOI: 10.6084/m9.figshare.5104873.v1
Patent number: US07091222B2

Linked notes

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