Hydrazine hydrate (1:1) → N-(3-Methyl-isoxazol-5-yl)-hydrazinecarboxamide
Reaction equation
O.[NH2:2][NH2:3].C1([O:10][C:11](=O)[NH:12][C:13]2[O:17][N:16]=[C:15]([CH3:18])[CH:14]=2)C=CC=CC=1>C(O)C>[CH3:18][C:15]1[CH:14]=[C:13]([NH:12][C:11]([NH:2][NH2:3])=[O:10])[O:17][N:16]=1Participants
4
Reactant 2
Product 1
Reagents, catalysts & solvents 1
Procedure
Hydrazine hydrate (95 μl) was added to a mixture of (3-methyl-isoxazol-5-yl)-carbamic acid phenyl ester (CA 81479-55-2) (417 mg) and ethanol (5 ml), and the resulting mixture was stirred overnight at room temperature. The precipitate was collected by filtration to obtain the title compound (100 mg).
Workup
- filtrationThe precipitate was collected by filtration
Sources & evidence
- ORD record
- ord-b9750ba282474cbc9934fa597714b169
- Source dataset
- uspto-grants-2012_08
- Patent number
- US08252810B2
Reaction notes
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