4-Pyridinecarboxaldehyde → HCID 12161434, compound

HRID 890898

Reaction equation

[N:1]1[CH:6]=[CH:5][C:4]([CH:7]=[O:8])=[CH:3][CH:2]=1.[Se:9]1[CH:13]=[CH:12][CH:11]=[CH:10]1>>[N:1]1[CH:6]=[CH:5][C:4]([CH:7]([OH:8])[C:10]2[Se:9][C:13]([CH:7]([C:4]3[CH:5]=[CH:6][N:1]=[CH:2][CH:3]=3)[OH:8])=[CH:12][CH:11]=2)=[CH:3][CH:2]=1

Participants

Reactant 2

HCID 133894-Pyridinecarboxaldehyde

HCID 136130Selenophene

Product 1

HCID 12161434HCID 12161434, compound

Procedure

2,5-bis(4-pyridylhydroxymethyl)selenophene was prepared by a reaction of 9.04 mL (0.09 mol) 4-pyrdinecarboxaldehyde with 3.5 mL (0.04 mol) selenophene by a procedure similar to that described above. The 2,5-bis(4-pyridylhydroxymethyl)selenophene was obtained in 20% yield. 1H NMR (DMSO-d6) δ 8.48 (d, J=3.4 Hz, 4H), 7.36 (d, J=3.4 Hz, 2H), 7 6.87 (s, 2H), 6.93 (s, 2H), 6.44 (brs, 2H), 5.82 (s, 2H); HRMS (FAB) (M+) calcd. for C16H15O2N2Se: 347.0299; found, 347.0301.

Sources & evidence

ORD record: ord-99e6887927ff4e1dbc612e76c14c68de
Source dataset: uspto-grants-2006_02
DOI: 10.6084/m9.figshare.5104873.v1
Patent number: US07001588B2

Linked notes

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