Acetic Acid → 3-(2,6-Dichloro-3-fluoro-benzyloxy)-pyridin-2-ylamine

HRID 89226

Reaction equation

[C:1]([OH:2])(=[O:3])[CH3:4].[CH3:36][CH2:37][O:38][CH2:39][CH3:40].[CH3:5][CH2:6][OH:7].[Cl:8][c:9]1[c:10]([CH2:11][O:12][c:13]2[c:14]([N+:19]([O-:20])=[O:21])[n:15][cH:16][cH:17][cH:18]2)[c:22]([Cl:27])[cH:23][cH:24][c:25]1[F:26].[Fe:34].[Na+:28].[Na+:29].[O-:30][C:31](=[O:32])[O-:33].[OH2:35]>>[Cl:8][c:9]1[c:10]([CH2:11][O:12][c:13]2[c:14]([NH2:19])[n:15][cH:16][cH:17][cH:18]2)[c:22]([Cl:27])[cH:23][cH:24][c:25]1[F:26]

Participants

Reactant 8

HCID 3283Diethyl Ether

HCID 19660Carbonate Ion

HCID 23925Iron

HCID 211113993-(2,6-Dichloro-3-fluoro-benzyloxy)-2-nitro-pyridine

Product 1

HCID 211114003-(2,6-Dichloro-3-fluoro-benzyloxy)-pyridin-2-ylamine

Sources & evidence

ORD record: ord-178468b4b6c54db38cd9aedd69ad7660
Source dataset: Training data from https://doi.org/10.1039/C8SC04228D (2/10)
DOI: 10.1039/C8SC04228D

Linked notes

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