Sodium Iodide → Cyclohexyloxycarbonyloxymethyl iodide
Reaction equation
[C:1](=[O:12])([O:5][CH:6]1[CH2:11][CH2:10][CH2:9][CH2:8][CH2:7]1)[O:2][CH2:3]Cl.[I-:13].[Na+]>CC(C)=O>[C:1](=[O:12])([O:5][CH:6]1[CH2:11][CH2:10][CH2:9][CH2:8][CH2:7]1)[O:2][CH2:3][I:13]Participants
4
Reactant 2
Product 1
Reagents, catalysts & solvents 1
Procedure
A solution of 0.78 g of chloromethyl cyclohexyl carbonate and 1.0 g of sodium iodide in 15 ml of acetone is stirred at room temperature for 16 hours and then concentrated under reduced pressure. The residue is extracted with ether and the solvent is distilled off under reduced pressure to give the title compound as pale yellow oil.
Workup
- concentrationconcentrated under reduced pressure
- extractionThe residue is extracted with ether
- distillationthe solvent is distilled off under reduced pressure
Sources & evidence
- ORD record
- ord-f6f0345371204717bf40763b7b156307
- Source dataset
- uspto-grants-1992_06
- Patent number
- US05120841
Reaction notes
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