1,2-Dibromopropane → 1,3-Bis(4'-methoxyphenyl)-2-imino-4-methyl-imidazolidine

HRID 894597

Reaction equation

[CH3:1][O:2][C:3]1[CH:8]=[CH:7][C:6]([NH:9][CH2:10][CH:11]([NH:13][C:14]2[CH:19]=[CH:18][C:17]([O:20][CH3:21])=[CH:16][CH:15]=2)[CH3:12])=[CH:5][CH:4]=1.COC1C=C[C:27]([NH2:28])=CC=1.BrCC(Br)C>>[CH3:1][O:2][C:3]1[CH:8]=[CH:7][C:6]([N:9]2[CH2:10][CH:11]([CH3:12])[N:13]([C:14]3[CH:15]=[CH:16][C:17]([O:20][CH3:21])=[CH:18][CH:19]=3)[C:27]2=[NH:28])=[CH:5][CH:4]=1

Participants

Reactant 3

HCID 65531,2-Dibromopropane

HCID 7732P-Anisidine

HCID 205124391,2-Bis(4'-methoxyphenyl-amino)-propane

Product 1

HCID 138814601,3-Bis(4'-methoxyphenyl)-2-imino-4-methyl-imidazolidineYield 32.7%

Procedure

1,2-Bis(4'-methoxyphenyl-amino)-propane, applied as starting substance, is obtained with a yield of 32.7% by reacting 4-methoxyaniline with 1,2-dibromopropane as described by McKay and Tarlton (loc. cit.). The compound melts at 82°-84° C.

Workup

customis obtained with a yield of 32.7%

Sources & evidence

ORD record: ord-de8e557985ee4d19975c5493df9169d8
Source dataset: uspto-grants-1981_08
DOI: 10.6084/m9.figshare.5104873.v1
Patent number: US04284642

Linked notes

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