2-Amino-4-methylpyridine → 2-(3,4-Dimethoxyphenyl)-7-methylimidazo(1,2-A)pyridine

HRID 895452

Reaction equation

HRID 895452 reaction equation
[NH2:1][C:2]1[CH:7]=[C:6]([CH3:8])[CH:5]=[CH:4][N:3]=1.[CH3:9][O:10][C:11]1[CH:12]=[C:13]([CH:18]=[CH:19][C:20]=1[O:21][CH3:22])[C:14](=O)[CH2:15]Br>>[CH3:9][O:10][C:11]1[CH:12]=[C:13]([C:14]2[N:1]=[C:2]3[CH:7]=[C:6]([CH3:8])[CH:5]=[CH:4][N:3]3[CH:15]=2)[CH:18]=[CH:19][C:20]=1[O:21][CH3:22]

Participants

3

Reactant 2

HCID 15332-Amino-4-methylpyridineHCID 2704232-Bromo-1-(3,4-dimethoxyphenyl)ethan-1-one

Product 1

HCID 98351272-(3,4-Dimethoxyphenyl)-7-methylimidazo(1,2-A)pyridine

Procedure

The title compound, pale yellow solid, m.p. 163° C. and MS: m/e=268.1 (M+), was prepared in accordance with the general method of example 1 from 2-amino-4-methyl-pyridine and 3,4-dimethoxy-phenacylbromide.

Sources & evidence

ORD record
ord-92ebbf9ab99f42cf967f66593f2093da
Source dataset
uspto-grants-2005_07
Patent number
US06916826B2

Linked notes

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