Sodium ion → 5-Bromo-2-(4-fluoro-benzyloxy)-pyridine

HRID 89591

Reaction equation

HRID 89591 reaction equation
[Br:17][c:18]1[n:19][cH:20][c:21]([Br:24])[cH:22][cH:23]1.[CH3:1][N:2]([CH3:3])[CH:4]=[O:5].[F:6][c:7]1[cH:8][cH:9][c:10]([CH2:11][OH:12])[cH:13][cH:14]1.[H-:15].[Na+:16].[OH2:25]>>[F:6][c:7]1[cH:8][cH:9][c:10]([CH2:11][O:12][c:18]2[n:19][cH:20][c:21]([Br:24])[cH:22][cH:23]2)[cH:13][cH:14]1

Participants

7

Reactant 6

HCID 923Sodium ionHCID 962WaterHCID 6228DimethylformamideHCID 680224-Fluorobenzylic alcoholHCID 693532,5-DibromopyridineHCID 166653Hydride

Product 1

HCID 592555025-Bromo-2-(4-fluoro-benzyloxy)-pyridine

Sources & evidence

ORD record
ord-21c60e2d1dae4598a1503a6f0b4afe1d
Source dataset
Training data from https://doi.org/10.1039/C8SC04228D (2/10)

Linked notes

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