2-Methylindole → Dimethyl-[(2-methyl-1H-indol-3-yl)-phenylmethyl]-amine

HRID 8986

Reaction equation

HRID 8986 reaction equation
[CH3:1][C:2]1[NH:3][C:4]2[C:9]([CH:10]=1)=[CH:8][CH:7]=[CH:6][CH:5]=2.[Cl-].[CH:12](=[N+:19]([CH3:21])[CH3:20])[C:13]1[CH:18]=[CH:17][CH:16]=[CH:15][CH:14]=1>>[CH3:20][N:19]([CH3:21])[CH:12]([C:10]1[C:9]2[C:4](=[CH:5][CH:6]=[CH:7][CH:8]=2)[NH:3][C:2]=1[CH3:1])[C:13]1[CH:18]=[CH:17][CH:16]=[CH:15][CH:14]=1

Participants

3

Reactant 2

HCID 72242-MethylindoleHCID 11073839Methanaminium, N-methyl-N-(phenylmethylene)-, chloride

Product 1

HCID 9921470Dimethyl-[(2-methyl-1H-indol-3-yl)-phenylmethyl]-amine

Procedure

The preparation was carried out in accordance with general synthesis instructions 4 from 2-methyl-1H-indole and benzylidene-dimethyl-ammonium chloride, which had been prepared in accordance with example 1.

Workup

  1. customhad been prepared in accordance with example 1

Sources & evidence

ORD record
ord-e385ae51537746cd8962eb40b5c4ef0d
Source dataset
uspto-grants-2006_08
Patent number
US07091220B2

Linked notes

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