5-Chloroindole → [(5-Chloro-1H-indol-3-yl)-phenylmethyl]-dimethylamine

HRID 8988

Reaction equation

HRID 8988 reaction equation
[Cl:1][C:2]1[CH:3]=[C:4]2[C:8](=[CH:9][CH:10]=1)[NH:7][CH:6]=[CH:5]2.[Cl-].[CH:12](=[N+:19]([CH3:21])[CH3:20])[C:13]1[CH:18]=[CH:17][CH:16]=[CH:15][CH:14]=1>>[Cl:1][C:2]1[CH:3]=[C:4]2[C:8](=[CH:9][CH:10]=1)[NH:7][CH:6]=[C:5]2[CH:12]([N:19]([CH3:21])[CH3:20])[C:13]1[CH:18]=[CH:17][CH:16]=[CH:15][CH:14]=1

Participants

3

Reactant 2

HCID 871105-ChloroindoleHCID 11073839Methanaminium, N-methyl-N-(phenylmethylene)-, chloride

Product 1

HCID 9814391[(5-Chloro-1H-indol-3-yl)-phenylmethyl]-dimethylamine

Procedure

The preparation was carried out in accordance with general synthesis instructions 4 from 5-chloro-1H-indole and benzylidene-dimethyl-ammonium chloride, which had been prepared in accordance with example 1.

Workup

  1. customhad been prepared in accordance with example 1

Sources & evidence

ORD record
ord-15cb9b2285214b0198c4d91d20a3fcb1
Source dataset
uspto-grants-2006_08
Patent number
US07091220B2

Linked notes

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