Bromide ion → tert-Butyl 4-(1-hydroxy-1-methyl-3-phenylprop-2-ynyl)piperidine-1-carboxylate

HRID 89982

Reaction equation

HRID 89982 reaction equation
[Br-:17].[C:1]([CH3:2])([CH3:3])([CH3:4])[O:5][C:6](=[O:7])[N:8]1[CH2:9][CH2:10][CH:11]([C:14]([CH3:15])=[O:16])[CH2:12][CH2:13]1.[CH2:27]1[O:28][CH2:29][CH2:30][CH2:31]1.[c:18]1([C:24]#[C:25][Mg+:26])[cH:19][cH:20][cH:21][cH:22][cH:23]1>>[C:1]([CH3:2])([CH3:3])([CH3:4])[O:5][C:6](=[O:7])[N:8]1[CH2:9][CH2:10][CH:11]([C:14]([CH3:15])([OH:16])[C:25]#[C:24][c:18]2[cH:19][cH:20][cH:21][cH:22][cH:23]2)[CH2:12][CH2:13]1

Participants

5

Reactant 4

HCID 259Bromide ionHCID 8028TetrahydrofuranHCID 109879834-Acetyl-piperidine-1-carboxylic acid tert-butyl esterHCID 178507028HCID 178507028, compound

Product 1

HCID 68725969tert-Butyl 4-(1-hydroxy-1-methyl-3-phenylprop-2-ynyl)piperidine-1-carboxylate

Sources & evidence

ORD record
ord-f143acdada64487eb1eef4844c769901
Source dataset
Training data from https://doi.org/10.1039/C8SC04228D (2/10)

Linked notes

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