((2-((6-Bromohexyl)oxy)ethoxy)methyl)benzene → 2-[(6-Bromohexyl)oxy]ethanol
Reaction equation
[Br:1][CH2:2][CH2:3][CH2:4][CH2:5][CH2:6][CH2:7][O:8][CH2:9][CH2:10][O:11]CC1C=CC=CC=1>CCOC(C)=O.CCO.[Pd]>[Br:1][CH2:2][CH2:3][CH2:4][CH2:5][CH2:6][CH2:7][O:8][CH2:9][CH2:10][OH:11]Participants
5
Reactant 1
Product 1
Reagents, catalysts & solvents 3
Procedure
A solution of [(2-[(6-bromohexyl)oxy]ethoxy)methyl]benzene (1.5 g) in EtOAc (20 ml) and EtOH (20 ml) was hydrogenated over 10% palladium on carbon (200 mg). After 2 h the mixture was filtered through celite and the filtrate evaporated in vacuo to give the title compound (1.05 g). TSP+ve 242 (MNH4)+, 244 (MNH4)+
Workup
- filtrationAfter 2 h the mixture was filtered through celite
- customthe filtrate evaporated in vacuo
Sources & evidence
- ORD record
- ord-b8cf140a618e43f5a8ffc7c32e7c4d28
- Source dataset
- uspto-grants-2008_04
- Patent number
- US07361787B2
Reaction notes
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