Dimethylamine → 2-Methoxy-benzylidene-dimethyl-ammonium chloride

HRID 9027

Reaction equation

HRID 9027 reaction equation
[CH3:1][NH:2][CH3:3].[CH3:4][O:5][C:6]1[CH:13]=[CH:12][CH:11]=[CH:10][C:7]=1[CH:8]=O.C([Cl:17])(=O)C>>[Cl-:17].[CH3:4][O:5][C:6]1[CH:13]=[CH:12][CH:11]=[CH:10][C:7]=1[CH:8]=[N+:2]([CH3:3])[CH3:1]

Participants

4

Reactant 3

HCID 674DimethylamineHCID 6367Acetyl chlorideHCID 86582-Methoxybenzaldehyde

Product 1

HCID 219853032-Methoxy-benzylidene-dimethyl-ammonium chloride

Procedure

The reaction of 17.0 ml (0.135 mol) dimethylamine solution and 6.8 g ml (0.050 mol) 2-methoxybenzaldehyde in accordance with general synthesis instructions 1 and subsequent reaction with 3.0 ml (0.050 mol) acetyl chloride in accordance with general synthesis instructions 3 gave 4.8 g (corresponding to 48% of the yield calculated by theory) 2-methoxy-benzylidene-dimethyl-ammonium chloride.

Workup

  1. customwith general synthesis instructions 3

Sources & evidence

ORD record
ord-6fc688613ae646f2a32ab26807d5074f
Source dataset
uspto-grants-2006_08
Patent number
US07091220B2

Linked notes

Loading…