2-Methylindole → [(2-Methoxyphenyl)-(2-methyl-1H-indol-3-yl)-methyl]-dimethylamine

HRID 9028

Reaction equation

[CH3:1][C:2]1[NH:3][C:4]2[C:9]([CH:10]=1)=[CH:8][CH:7]=[CH:6][CH:5]=2.[Cl-].[CH3:12][O:13][C:14]1[CH:23]=[CH:22][CH:21]=[CH:20][C:15]=1[CH:16]=[N+:17]([CH3:19])[CH3:18]>>[CH3:12][O:13][C:14]1[CH:23]=[CH:22][CH:21]=[CH:20][C:15]=1[CH:16]([N:17]([CH3:18])[CH3:19])[C:10]1[C:9]2[C:4](=[CH:5][CH:6]=[CH:7][CH:8]=2)[NH:3][C:2]=1[CH3:1]

Participants

Reactant 2

HCID 72242-Methylindole

HCID 219853032-Methoxy-benzylidene-dimethyl-ammonium chloride

Product 1

HCID 9857311[(2-Methoxyphenyl)-(2-methyl-1H-indol-3-yl)-methyl]-dimethylamine

Procedure

The preparation was carried out in accordance with general synthesis instructions 4 from 2-methyl-1H-indole and (2-methoxy-benzylidene)-dimethyl-ammonium chloride.

Sources & evidence

ORD record: ord-c2c231d55e2b4f149603923349bae181
Source dataset: uspto-grants-2006_08
DOI: 10.6084/m9.figshare.5104873.v1
Patent number: US07091220B2

Linked notes

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