Ethanol → 2-Chloro-4-ethoxy-6-dimethylamino-1,3,5-triazine

HRID 903321Notes

Reaction equation

HRID 903321 reaction equation
[Na].ClC1N=NN=C(Cl)C=1.[Cl:10][C:11]1[N:16]=[C:15](Cl)[N:14]=[C:13]([N:18]([CH3:20])[CH3:19])[N:12]=1.[CH2:21]([OH:23])[CH3:22]>>[Cl:10][C:11]1[N:16]=[C:15]([O:23][CH2:21][CH3:22])[N:14]=[C:13]([N:18]([CH3:20])[CH3:19])[N:12]=1

Participants

5

Reactant 4

HCID 702Ethanol2×HCID 169852,4-Dichloro-6-(dimethylamino)-1,3,5-triazineHCID 5360545SodiumHCID 18348308HCID 18348308, compound

Product 1

HCID 233381422-Chloro-4-ethoxy-6-dimethylamino-1,3,5-triazine

Procedure

A solution of sodium (0.46 g.) in ethanol (50 ml.) was added with stirring and waterbath cooling (25° C.) to a solution of the dichlorotriazine (3.86 g.) from (a) in ethanol (50 ml.). Following the addition the solution was poured into ice water (250 ml.) and the product collected, dried and crystallised from petroleum as needles (2.5 g.) having a melting point of 124° C.

Workup

  1. additionthe addition the solution
  2. customthe product collected
  3. customdried
  4. customcrystallised from petroleum as needles (2.5 g.)

Sources & evidence

ORD record
ord-66b37f85eaa14fb1b300dbb4ab41495e
Source dataset
uspto-grants-1980_10
Patent number
US04226990

Reaction notes

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