Isopropylamine → N-Isopropylmethacrylamide

HRID 903519

Reaction equation

HRID 903519 reaction equation
[C:1]([O:6]C)(=O)[C:2]([CH3:4])=[CH2:3].[CH:8]([NH2:11])([CH3:10])[CH3:9]>>[CH:8]([NH:11][C:1](=[O:6])[C:2]([CH3:4])=[CH2:3])([CH3:10])[CH3:9]

Participants

3

Reactant 2

HCID 6363IsopropylamineHCID 6658Methyl Methacrylate

Product 1

HCID 83698N-IsopropylmethacrylamideYield 32%

Procedure

200 g of methyl methacrylate and 142 g of isopropylamine were heated at 190° C. for 21/2 hours in a 0.5-liter stirred autoclave (pmax =15 atmospheres). N-isopropyl-methacrylic acid amide was formed in this way in a 32% yield.

Sources & evidence

ORD record
ord-8bd2f0698eaf4139be03c1b377c0d6eb
Source dataset
uspto-grants-1980_10
Patent number
US04228102

Linked notes

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