1-Butanol → HCID 178492027, compound
Reaction equation
[CH3:1][O:2][C:3]1[CH:8]=[CH:7][C:6]([NH:9][NH:10][C:11](=[S:13])[NH2:12])=[CH:5][CH:4]=1.[C:14](O)(=O)C.C(=N)N.C(O)CCC.O(C(C)C)C(C)C>O>[CH3:1][O:2][C:3]1[CH:4]=[CH:5][C:6]([N:9]2[CH:14]=[N:12][C:11]([SH:13])=[N:10]2)=[CH:7][CH:8]=1Participants
6
Reactant 4
Product 1
Reagents, catalysts & solvents 1
Procedure
A mixture of 10 parts of 2-(4-methoxyphenyl)-hydrazinecarbothioamide, 10.6 parts of methanimidamide acetate and 80 parts of 1-butanol is stirred and refluxed for 1 hour. After cooling, water and 2,2'-oxybispropane are added, whereupon the product is precipitated. It is filtered off and dried, yielding 7.6 parts (73%) of 1-(4-methoxyphenyl)-1H-1,2,4-triazole-3-thiol.
Workup
- temperaturerefluxed for 1 hour
- temperatureAfter cooling
- customis precipitated
- filtrationIt is filtered off
- customdried
Sources & evidence
- ORD record
- ord-b88711fa01de4b2195d93bc9f17e8188
- Source dataset
- uspto-grants-1980_10
- Patent number
- US04229460
Reaction notes
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