Acetic Anhydride → HCID 9859076, compound
Reaction equation
[N:1](=[C:3]1[CH2:12][CH2:11][C:10]2[C:5](=[CH:6][CH:7]=[CH:8][CH:9]=2)[CH2:4]1)O.[C:13](OC(=O)C)(=[O:15])[CH3:14].[O:20]1CCCC1>[Pd]>[C:13]([NH:1][CH:3]1[CH2:12][CH2:11][C:10]2[C:5](=[CH:6][CH:7]=[CH:8][CH:9]=2)[C:4]1=[O:20])(=[O:15])[CH3:14]Participants
5
Reactant 3
Product 1
Reagents, catalysts & solvents 1
Procedure
A slurry of 2-oximino-3,4-dihydronaphthalen-[1(2H)-one (8.75 gm, 0.05 m) acetic anhydride (25 ml), tetrahydrofuran (150 ml) and Pd/C (10%, 500 mg) was hydrogenated on a Parr apparatus for 3 hours. The catalyst was removed by filtration through diatomaceous earth. The organic solvents were evaporated under reduced pressure (20 mm) to yield the product as an oil, which was used in the next step without further purification.
Workup
- customThe catalyst was removed by filtration through diatomaceous earth
- customThe organic solvents were evaporated under reduced pressure (20 mm)
Sources & evidence
- ORD record
- ord-74327dc6bb1e4c6e844b4c077bc9bd0a
- Source dataset
- uspto-grants-1983_12
- Patent number
- US04420480
Reaction notes
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