4-Methoxybenzylamine → (+/-)-4-[(3,5-Dichloro-4-pyridyl)aminocarbonyl]-7-methoxy-3-[(4-methoxybenzyl)aminocarbonyl]methyl-2,3-dihydrobenzofuran

HRID 90631

Reaction equation

HRID 90631 reaction equation
[C:1](=[O:2])([OH:3])[CH2:4][CH:5]1[CH2:6][O:7][c:8]2[c:9]1[c:10]([C:16](=[O:17])[NH:18][c:19]1[c:20]([Cl:26])[cH:21][n:22][cH:23][c:24]1[Cl:25])[cH:11][cH:12][c:13]2[O:14][CH3:15].[CH3:27][O:28][c:29]1[cH:30][cH:31][c:32]([CH2:33][NH2:34])[cH:35][cH:36]1>>[C:1](=[O:2])([CH2:4][CH:5]1[CH2:6][O:7][c:8]2[c:9]1[c:10]([C:16](=[O:17])[NH:18][c:19]1[c:20]([Cl:26])[cH:21][n:22][cH:23][c:24]1[Cl:25])[cH:11][cH:12][c:13]2[O:14][CH3:15])[NH:34][CH2:33][c:32]1[cH:31][cH:30][c:29]([O:28][CH3:27])[cH:36][cH:35]1

Participants

3

Reactant 2

HCID 754524-MethoxybenzylamineHCID 22734342(+/-)-3-Carboxymethyl-4-(3,5-dichloro-4-pyridylamino-carbonyl)-7-methoxy-2,3-dihydrobenzofuran

Product 1

HCID 22734482(+/-)-4-[(3,5-Dichloro-4-pyridyl)aminocarbonyl]-7-methoxy-3-[(4-methoxybenzyl)aminocarbonyl]methyl-2,3-dihydrobenzofuran

Sources & evidence

ORD record
ord-14a6a4583d884b05974081cc577de957
Source dataset
Training data from https://doi.org/10.1039/C8SC04228D (2/10)

Linked notes

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