Tetrahydrofuran → Tert-butyl 3-(3-bromophenyl)-3-hydroxypiperidine-1-carboxylate
Reaction equation
[Br:6][c:7]1[cH:8][c:9]([I:13])[cH:10][cH:11][cH:12]1.[C:14](=[O:15])([O:16][C:17]([CH3:18])([CH3:19])[CH3:20])[N:21]1[CH2:22][C:23](=[O:27])[CH2:24][CH2:25][CH2:26]1.[CH2:1]([Li:2])[CH2:3][CH2:4][CH3:5].[CH2:28]1[O:29][CH2:30][CH2:31][CH2:32]1>>[Br:6][c:7]1[cH:8][c:9]([C:23]2([OH:27])[CH2:22][N:21]([C:14](=[O:15])[O:16][C:17]([CH3:18])([CH3:19])[CH3:20])[CH2:26][CH2:25][CH2:24]2)[cH:10][cH:11][cH:12]1Participants
5
Sources & evidence
- ORD record
- ord-b35044b5e7bc48faac8344e1bf849851
- Source dataset
- Training data from https://doi.org/10.1039/C8SC04228D (2/10)
Reaction notes
Loading…