Hydrochloric Acid → HCID 86594427, compound

Reaction equation

[CH3:1][O:2][C:3](=[O:21])[C@@H:4]([NH:13]C(OC(C)(C)C)=O)[CH2:5][CH2:6][N:7]([CH2:9][CH2:10][O:11][CH3:12])[CH3:8].[ClH:22]>>[ClH:22].[ClH:22].[CH3:1][O:2][C:3](=[O:21])[C@@H:4]([NH2:13])[CH2:5][CH2:6][N:7]([CH2:9][CH2:10][O:11][CH3:12])[CH3:8]

Participants

Reactant 2

HCID 313Hydrochloric Acid

HCID 86594426HCID 86594426, compound

Product 1

HCID 86594427HCID 86594427, compound

Procedure

(S)-2-tert-Butoxycarbonylamino-4-[(2-methoxyethyl)-methylamino]-butyric acid methyl ester (0.086 g, 0.28 mmol) was treated with HCl (1 mL of 4M in dioxane) and sonicated. The mixture was concentrated and dried under high vacuum to provide the product.

Workup

customsonicated
concentrationThe mixture was concentrated
customdried under high vacuum
customto provide the product

Sources & evidence

ORD record: ord-c6b75837598e49c4b14507a8a40a53dd
Source dataset: uspto-grants-2011_09
DOI: 10.6084/m9.figshare.5104873.v1
Patent number: US08017641B2

Reaction notes

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