Reaction equation
Br[C:2]1[CH:7]=[CH:6][C:5]([S:8]([CH2:11][CH3:12])(=[O:10])=[O:9])=[C:4]([C:13]([F:16])([F:15])[F:14])[CH:3]=1.[NH2:17][C:18]1[CH:23]=[CH:22][C:21]([Cl:24])=[CH:20][C:19]=1[OH:25]>>[Cl:24][C:21]1[CH:22]=[CH:23][C:18]([NH2:17])=[C:19]([O:25][C:2]2[CH:7]=[CH:6][C:5]([S:8]([CH2:11][CH3:12])(=[O:10])=[O:9])=[C:4]([C:13]([F:16])([F:15])[F:14])[CH:3]=2)[CH:20]=1Participants
3
Procedure
The subtitle compound was prepared by the example 3 step viii) using the product from example 22 step i) and 2-amino-5-chlorophenol. Yield 11.0 g
Sources & evidence
- ORD record
- ord-5abb6f6abf174c1892f0c1f9cd0623c0
- Source dataset
- uspto-grants-2011_09
- Patent number
- US08022248B2
Linked notes
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