Hydrochloric Acid → 1-(5-Bromo-3-(tert-butyl)-2-methoxyphenyl]piperazine

HRID 91241

Reaction equation

HRID 91241 reaction equation
[Br:1][c:2]1[cH:3][c:4]([C:11]([CH3:12])([CH3:13])[CH3:14])[c:5]([O:9][CH3:10])[c:6]([NH2:7])[cH:8]1.[C:23](=[O:24])([O-:25])[O-:26].[Cl:16][CH2:17][CH2:18][NH:19][CH2:20][CH2:21][Cl:22].[Cl:30][c:31]1[c:32]([Cl:33])[cH:34][cH:35][cH:36][cH:37]1.[ClH:15].[K+:27].[K+:28].[OH2:29]>>[Br:1][c:2]1[cH:3][c:4]([C:11]([CH3:12])([CH3:13])[CH3:14])[c:5]([O:9][CH3:10])[c:6]([N:7]2[CH2:17][CH2:18][NH:19][CH2:20][CH2:21]2)[cH:8]1

Participants

8

Reactant 7

HCID 313Hydrochloric AcidHCID 813Potassium Cation2×HCID 962WaterHCID 72391,2-DichlorobenzeneHCID 9533Bis(2-chloroethyl)amineHCID 19660Carbonate IonHCID 229301555-Bromo-3-tert-butyl-2-methoxyaniline

Product 1

HCID 589099601-(5-Bromo-3-(tert-butyl)-2-methoxyphenyl]piperazine

Sources & evidence

ORD record
ord-b8a292aec027415296e85cc326f36a4a
Source dataset
Training data from https://doi.org/10.1039/C8SC04228D (2/10)

Linked notes

Loading…