Ammonia → 5-(2,6-difluorophenyl)-3-{[1-(trifluoromethanesulphonyl)piperidin-4-yl]amino}-1H-pyrazolo[4,3-c]isoquinoline-7-carboxamide
Reaction equation
[Cl:54][CH2:55][Cl:56].[F:1][c:2]1[c:3](-[c:9]2[n:10][c:11]3[c:12]([c:13]4[cH:14][cH:15][c:16]([C:19](=[O:20])[NH2:21])[cH:17][c:18]24)[n:22]([CH2:39][O:40][CH2:41][CH2:42][Si:43]([CH3:44])([CH3:45])[CH3:46])[n:23][c:24]3[NH:25][CH:26]2[CH2:27][CH2:28][N:29]([S:32](=[O:33])(=[O:34])[C:35]([F:36])([F:37])[F:38])[CH2:30][CH2:31]2)[c:4]([F:8])[cH:5][cH:6][cH:7]1.[F:47][C:48]([F:49])([F:50])[C:51]([OH:52])=[O:53].[NH3:58].[OH2:57]>>[F:1][c:2]1[c:3](-[c:9]2[n:10][c:11]3[c:12]([c:13]4[cH:14][cH:15][c:16]([C:19](=[O:20])[NH2:21])[cH:17][c:18]24)[nH:22][n:23][c:24]3[NH:25][CH:26]2[CH2:27][CH2:28][N:29]([S:32](=[O:33])(=[O:34])[C:35]([F:36])([F:37])[F:38])[CH2:30][CH2:31]2)[c:4]([F:8])[cH:5][cH:6][cH:7]1
