Sodium ion → tert-Butyl 2-(diethoxyphosphoryl)-3-(1,3-thiazol-4-yl)propanoate

HRID 91618

Reaction equation

HRID 91618 reaction equation
[Br:19][CH2:20][c:21]1[n:22][cH:23][s:24][cH:25]1.[CH2:1]([CH3:2])[O:3][P:4](=[O:5])([O:6][CH2:7][CH3:8])[CH2:9][C:10](=[O:11])[O:12][C:13]([CH3:14])([CH3:15])[CH3:16].[CH3:26][N:27]([CH3:28])[CH:29]=[O:30].[CH3:31][c:32]1[cH:33][cH:34][cH:35][cH:36][cH:37]1.[H-:17].[Na+:18]>>[CH2:1]([CH3:2])[O:3][P:4](=[O:5])([O:6][CH2:7][CH3:8])[CH:9]([C:10](=[O:11])[O:12][C:13]([CH3:14])([CH3:15])[CH3:16])[CH2:20][c:21]1[n:22][cH:23][s:24][cH:25]1

Participants

7

Reactant 6

HCID 923Sodium ionHCID 1140TolueneHCID 6228DimethylformamideHCID 166653HydrideHCID 2773685tert-Butyl diethylphosphonoacetateHCID 98989844-(Bromomethyl)thiazole

Product 1

HCID 86602109tert-Butyl 2-(diethoxyphosphoryl)-3-(1,3-thiazol-4-yl)propanoate

Sources & evidence

ORD record
ord-924f5f8bfc734983af163dc6b8075dd1
Source dataset
Training data from https://doi.org/10.1039/C8SC04228D (2/10)

Linked notes

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