Hydrochloric Acid → 4-(2,4-Dioxo-8-oxa-1,3-diazaspiro[4.5]decan-3-yl)-2-(trifluoromethyl)-benzonitrile
Reaction equation
[CH3:25][OH:26].[CH:27]([Cl:28])([Cl:29])[Cl:30].[ClH:31].[NH:1]=[C:2]1[N:3]([c:13]2[cH:14][c:15]([C:21]([F:22])([F:23])[F:24])[c:16]([C:17]#[N:18])[cH:19][cH:20]2)[C:4](=[O:12])[NH:5][C:6]12[CH2:7][CH2:8][O:9][CH2:10][CH2:11]2.[OH2:32]>>[C:2]1(=[O:26])[N:3]([c:13]2[cH:14][c:15]([C:21]([F:22])([F:23])[F:24])[c:16]([C:17]#[N:18])[cH:19][cH:20]2)[C:4](=[O:12])[NH:5][C:6]12[CH2:7][CH2:8][O:9][CH2:10][CH2:11]2Participants
6
Sources & evidence
- ORD record
- ord-990e9e29d3e04a259f0268f997dc4fa8
- Source dataset
- Training data from https://doi.org/10.1039/C8SC04228D (2/10)
Reaction notes
Loading…