Hydrochloric Acid → (S)-2-amino-3-phenylpropan-1-ol hydrochloride

HRID 921985Notes

Reaction equation

HRID 921985 reaction equation
[NH2:1][C@@H:2]([CH2:5][C:6]1[CH:11]=[CH:10][CH:9]=[CH:8][CH:7]=1)[CH2:3][OH:4].[ClH:12]>O>[ClH:12].[NH2:1][C@@H:2]([CH2:5][C:6]1[CH:11]=[CH:10][CH:9]=[CH:8][CH:7]=1)[CH2:3][OH:4]

Participants

4

Reactant 2

HCID 313Hydrochloric AcidHCID 447213phenylalaninol, (S)-

Product 1

HCID 69017766(S)-2-amino-3-phenylpropan-1-ol hydrochloride

Reagents, catalysts & solvents 1

HCID 962WaterSolvent

Procedure

The salt (S)-(−)-2-amino-3-phenyl-1-propanol hydrochloride (RV 4) was obtained by dissolving (S)-(−)-2-amino-3-phenyl-1-propanol, obtained from Sigma-Aldrich (Aldrich ref. 190438, CAS#3182-95-4) in Milli-Q® water and by adding hydrochloric acid (HCl) so as to obtain a 992 mM solution of the (S)-(−)-2-amino-3-phenyl-1-propanol hydrochloride salt.

Sources & evidence

ORD record
ord-b24f9ed7a59446b786750ac8dc471f02
Source dataset
uspto-grants-2016_03
Patent number
US09278131B2

Reaction notes

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