Methanol → 4-(2,3-Dihydroindol-1-yl)-6-(4-amino-phenyl)-7H-pyrrolo[2,3-d]pyrimidine

Reaction equation

[CH2:30]1[O:31][CH2:32][CH2:33][CH2:34]1.[CH3:28][OH:29].[N:1]1([c:10]2[c:11]3[c:12]([n:13][cH:14][n:15]2)[nH:16][c:17](-[c:19]2[cH:20][cH:21][c:22]([N+:25]([O-:26])=[O:27])[cH:23][cH:24]2)[cH:18]3)[CH2:2][CH2:3][c:4]2[cH:5][cH:6][cH:7][cH:8][c:9]21>>[N:1]1([c:10]2[c:11]3[c:12]([n:13][cH:14][n:15]2)[nH:16][c:17](-[c:19]2[cH:20][cH:21][c:22]([NH2:25])[cH:23][cH:24]2)[cH:18]3)[CH2:2][CH2:3][c:4]2[cH:5][cH:6][cH:7][cH:8][c:9]21

Participants

Reactant 3

HCID 887Methanol

HCID 8028Tetrahydrofuran

HCID 232824614-(2,3-Dihydroindol-1-yl)-6-(4-nitro-phenyl)-7H-pyrrolo[2,3-d]pyrimidine

Product 1

HCID 232824604-(2,3-Dihydroindol-1-yl)-6-(4-amino-phenyl)-7H-pyrrolo[2,3-d]pyrimidine

Sources & evidence

ORD record: ord-72399287455e4f5bbd69fa15037aa96c
Source dataset: Training data from https://doi.org/10.1039/C8SC04228D (2/10)
DOI: 10.1039/C8SC04228D

Reaction notes

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