Acetic Acid → 8-(2,4-Dichloro-5-methoxyphenyl)-1,4-dioxa-8-azaspiro[4.5]decane
Reaction equation
[C:31]([OH:32])(=[O:33])[CH3:34].[Cl:1][c:2]1[c:3]([O:18][CH3:19])[cH:4][c:5]([N:8]2[CH2:9][CH2:10][C:11]3([O:12][CH2:13][CH2:14][O:15]3)[CH2:16][CH2:17]2)[cH:6][cH:7]1.[Cl:20][N:21]1[C:22](=[O:23])[CH2:24][CH2:25][C:26]1=[O:27].[Na+:30].[OH-:29].[OH2:28]>>[Cl:1][c:2]1[c:3]([O:18][CH3:19])[cH:4][c:5]([N:8]2[CH2:9][CH2:10][C:11]3([O:12][CH2:13][CH2:14][O:15]3)[CH2:16][CH2:17]2)[c:6]([Cl:20])[cH:7]1Participants
7
Sources & evidence
- ORD record
- ord-f827d620a16e4236aca5e90863a68c85
- Source dataset
- Validation data from https://doi.org/10.1039/C8SC04228D
Reaction notes
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