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Sodium Ion → 2,3-Dihydro-1H-indole-5-carbonitrile

HRID 934674
Notes
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Reaction equation

HRID 934674 reaction equation
[CH2:18]1[O:19][CH2:20][CH2:21][CH2:22]1.[F:1][C:2]([F:3])([F:4])[C:16]([N:5]1[CH2:6][CH2:7][c:8]2[cH:9][c:10]([C:14]#[N:15])[cH:11][cH:12][c:13]21)=[O:17].[Na+:24].[OH-:23]>>[NH:5]1[CH2:6][CH2:7][c:8]2[cH:9][c:10]([C:14]#[N:15])[cH:11][cH:12][c:13]21
ParticipantsSources & evidenceReaction notes

Participants

5

Reactant 4

HCID 923Sodium IonHCID 961HydroxideHCID 8028TetrahydrofuranHCID 866259911-(2,2,2-Trifluoroacetyl)indoline-5-carbonitrile

Product 1

HCID 219076392,3-Dihydro-1H-indole-5-carbonitrile

Sources & evidence

ORD record
ord-777d68c4ef3040e7bd71617a08695678
Source dataset
Validation data from https://doi.org/10.1039/C8SC04228D
DOI
10.1039/C8SC04228D

Reaction notes

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On this pageParticipantsSources & evidenceReaction notes