Sodium ion → 6-{trans-4-[3-(4-fluorophenyl)propylamino]cyclohexyl}-3H-benzthiazol-2-one

HRID 934706

Reaction equation

HRID 934706 reaction equation
[BH4-:29].[CH3:31][CH:32]([OH:33])[CH3:34].[F:18][c:19]1[cH:20][cH:21][c:22]([CH2:25][CH2:26][CH2:27][NH2:28])[cH:23][cH:24]1.[Na+:30].[O:1]=[C:2]1[CH2:3][CH2:4][CH:5]([c:8]2[cH:9][c:10]3[c:11]([nH:12][c:13](=[O:15])[s:14]3)[cH:16][cH:17]2)[CH2:6][CH2:7]1>>[CH:2]1([NH:28][CH2:27][CH2:26][CH2:25][c:22]2[cH:21][cH:20][c:19]([F:18])[cH:24][cH:23]2)[CH2:3][CH2:4][CH:5]([c:8]2[cH:9][c:10]3[c:11]([nH:12][c:13](=[O:15])[s:14]3)[cH:16][cH:17]2)[CH2:6][CH2:7]1

Participants

6

Reactant 5

HCID 923Sodium ionHCID 3776IsopropanolHCID 28123BorohydrideHCID 64837963-(4-Fluorophenyl)propan-1-amineHCID 226691096-(4-oxocyclohexyl)-3H-benzothiazol-2-one

Product 1

HCID 226691456-{trans-4-[3-(4-fluorophenyl)propylamino]cyclohexyl}-3H-benzthiazol-2-one

Sources & evidence

ORD record
ord-458f8561b0ce44d5b9d1453dafa2d262
Source dataset
Validation data from https://doi.org/10.1039/C8SC04228D

Linked notes

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