Methanol → N-[2-(4-aminophenyl)ethyl]-2,2,2-trifluoro-N-[(3-fluorophenyl)methyl]acetamide
Reaction equation
[CH2:27]1[O:28][CH2:29][CH2:30][CH2:31]1.[CH3:32][OH:33].[F:1][c:2]1[cH:3][c:4]([CH2:8][N:9]([C:10]([C:11]([F:12])([F:13])[F:14])=[O:15])[CH2:16][CH2:17][c:18]2[cH:19][cH:20][c:21]([N+:24]([O-:25])=[O:26])[cH:22][cH:23]2)[cH:5][cH:6][cH:7]1>>[F:1][c:2]1[cH:3][c:4]([CH2:8][N:9]([C:10]([C:11]([F:12])([F:13])[F:14])=[O:15])[CH2:16][CH2:17][c:18]2[cH:19][cH:20][c:21]([NH2:24])[cH:22][cH:23]2)[cH:5][cH:6][cH:7]1Participants
4
Sources & evidence
- ORD record
- ord-4d44ba1ff2284e1b82e26840a273de5b
- Source dataset
- Validation data from https://doi.org/10.1039/C8SC04228D
Reaction notes
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