Hydrochloric Acid → 6-(4-Amino-2-fluorophenoxy)pyrimidin-4-amine
Reaction equation
[C:21](=[O:22])([O-:23])[O-:24].[CH3:27][OH:28].[ClH:20].[NH2:1][c:2]1[cH:3][c:4]([O:8][c:9]2[c:10]([F:19])[cH:11][c:12]([NH:15][C:16](=[O:17])[CH3:18])[cH:13][cH:14]2)[n:5][cH:6][n:7]1.[Na+:25].[Na+:26]>>[NH2:1][c:2]1[cH:3][c:4]([O:8][c:9]2[c:10]([F:19])[cH:11][c:12]([NH2:15])[cH:13][cH:14]2)[n:5][cH:6][n:7]1Participants
6
Sources & evidence
- ORD record
- ord-486c1e9399db4fa8807c561eb0f1c93b
- Source dataset
- Validation data from https://doi.org/10.1039/C8SC04228D
Reaction notes
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