Water → 4-(3-Hydroxy-2-methyl-5-oxopyrrolidin-1-yl)-2-(trifluoromethyl)benzonitrile
Reaction equation
[C:1]([Si:2]([CH3:3])([CH3:4])[O:6][CH:7]1[CH:8]([CH3:25])[N:9]([c:13]2[cH:14][c:15]([C:21]([F:22])([F:23])[F:24])[c:16]([C:17]#[N:18])[cH:19][cH:20]2)[C:10](=[O:12])[CH2:11]1)([CH3:5])([CH3:26])[CH3:27].[CH2:29]1[O:30][CH2:31][CH2:32][CH2:33]1.[OH2:28]>>[OH:6][CH:7]1[CH:8]([CH3:25])[N:9]([c:13]2[cH:14][c:15]([C:21]([F:22])([F:23])[F:24])[c:16]([C:17]#[N:18])[cH:19][cH:20]2)[C:10](=[O:12])[CH2:11]1Participants
4
Sources & evidence
- ORD record
- ord-eccf4ddb15b3431daa412249f6dcdd1d
- Source dataset
- Validation data from https://doi.org/10.1039/C8SC04228D
Reaction notes
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