Tetrahydrofuran → (3-Chloro-1-benzothien-2-yl)methanol

Reaction equation

[C:1]([Si:2]([O:3][CH:4]([CH2:5][CH2:14][c:15]1[c:16]([Cl:24])[c:17]2[c:18]([s:19]1)[cH:20][cH:21][cH:22][cH:23]2)[CH:6]=[CH:7][I:8])([CH3:9])[CH3:10])([CH3:11])([CH3:12])[CH3:13].[C:25]([Li:26])([CH3:27])([CH3:28])[CH3:29].[CH2:30]1[CH2:33][CH2:32][CH2:31][O:34]1>>[CH2:14]([c:15]1[c:16]([Cl:24])[c:17]2[c:18]([s:19]1)[cH:20][cH:21][cH:22][cH:23]2)[OH:34]

Participants

Reactant 3

HCID 8028Tetrahydrofuran

HCID 73856872Tert-butyl-[5-(3-chloro-1-benzothiophen-2-yl)-1-iodopent-1-en-3-yl]oxy-dimethylsilane

HCID 178418306HCID 178418306, compound

Product 1

HCID 821965(3-Chloro-1-benzothien-2-yl)methanol

Sources & evidence

ORD record: ord-4ec7403bda024256876e1ec6533da961
Source dataset: Validation data from https://doi.org/10.1039/C8SC04228D
DOI: 10.1039/C8SC04228D

Reaction notes

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