Dichloromethane → 4-(5-Benzyl-2-methyl-2H-pyrazol-3-yl)-piperidine

Reaction equation

[C:1]([O:2][C:3](=[O:4])[N:8]1[CH2:9][CH2:10][CH:11]([c:14]2[n:15]([CH3:26])[n:16][c:17]([CH2:19][c:20]3[cH:21][cH:22][cH:23][cH:24][cH:25]3)[cH:18]2)[CH2:12][CH2:13]1)([CH3:5])([CH3:6])[CH3:7].[Cl:34][CH2:35][Cl:36].[OH:27][C:28]([C:29]([F:30])([F:31])[F:32])=[O:33]>>[NH:8]1[CH2:9][CH2:10][CH:11]([c:14]2[n:15]([CH3:26])[n:16][c:17]([CH2:19][c:20]3[cH:21][cH:22][cH:23][cH:24][cH:25]3)[cH:18]2)[CH2:12][CH2:13]1

Participants

Reactant 3

HCID 6344Dichloromethane

HCID 6422Trifluoroacetic acid

HCID 69447489HCID 69447489, compound

Product 1

HCID 181876564-(5-Benzyl-2-methyl-2H-pyrazol-3-yl)-piperidine

Sources & evidence

ORD record: ord-a0bf45fde6c24d0281c69a6be0d2dc00
Source dataset: Validation data from https://doi.org/10.1039/C8SC04228D
DOI: 10.1039/C8SC04228D

Reaction notes

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