Acetic Acid → 6-Amino-3,3-bis-trifluoromethyl-1,3-dihydro-indol-2-one

Reaction equation

[C:21]([OH:22])(=[O:23])[CH3:24].[CH2:25]1[O:26][CH2:27][CH2:28][CH2:29]1.[NH2:1][c:2]1[cH:3][cH:4][c:5]2[c:9]([cH:10]1)[N:8]([OH:11])[C:7](=[O:12])[C:6]2([C:13]([F:14])([F:15])[F:16])[C:17]([F:18])([F:19])[F:20].[Zn:30]>>[NH2:1][c:2]1[cH:3][cH:4][c:5]2[c:9]([cH:10]1)[NH:8][C:7](=[O:12])[C:6]2([C:13]([F:14])([F:15])[F:16])[C:17]([F:18])([F:19])[F:20]