Ammonia → 2-amino-7-chloro-5-(2-pyridyl)-3H-1,4-benzodiazepine
Reaction equation
[CH3:2][OH:3].[Cl:4][c:5]1[cH:6][cH:7][c:8]2[c:9]([cH:22]1)[C:10]([c:16]1[n:17][cH:18][cH:19][cH:20][cH:21]1)=[N:11][CH2:12][C:13](=[S:15])[NH:14]2.[NH3:1].[O:23]1[CH2:24][CH2:25][CH2:26][CH2:27]1>>[NH2:1][C:13]1=[N:14][c:8]2[cH:7][cH:6][c:5]([Cl:4])[cH:22][c:9]2[C:10]([c:16]2[n:17][cH:18][cH:19][cH:20][cH:21]2)=[N:11][CH2:12]1Participants
5
Sources & evidence
- ORD record
- ord-57c494c1d4fc4636bd4337f3515523ac
- Source dataset
- Validation data from https://doi.org/10.1039/C8SC04228D
Reaction notes
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