N,N-Dimethylaniline → 4-Chloro-1-(2-fluoro-4-methanesulfonyl-phenyl)-1H-pyrazolo[3,4-d]pyrimidine

HRID 940048

Reaction equation

HRID 940048 reaction equation
[CH3:27][N:28]([CH3:29])[c:30]1[cH:31][cH:32][cH:33][cH:34][cH:35]1.[F:1][c:2]1[c:3](-[n:12]2[n:13][cH:14][c:15]3[c:16]2[n:17][cH:18][n:19][c:20]3[OH:21])[cH:4][cH:5][c:6]([S:8](=[O:9])(=[O:10])[CH3:11])[cH:7]1.[P:22]([Cl:23])([Cl:24])([Cl:25])=[O:26]>>[F:1][c:2]1[c:3](-[n:12]2[n:13][cH:14][c:15]3[c:16]2[n:17][cH:18][n:19][c:20]3[Cl:24])[cH:4][cH:5][c:6]([S:8](=[O:9])(=[O:10])[CH3:11])[cH:7]1

Participants

4

Reactant 3

HCID 949N,N-DimethylanilineHCID 24813Phosphorus oxychlorideHCID 178504786HCID 178504786, compound

Product 1

HCID 218976614-Chloro-1-(2-fluoro-4-methanesulfonyl-phenyl)-1H-pyrazolo[3,4-d]pyrimidine

Sources & evidence

ORD record
ord-848d132fabfd482d84a9b07a5e351015
Source dataset
Validation data from https://doi.org/10.1039/C8SC04228D

Linked notes

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