N-methyl-2-pyrrolidone → tert-Butyl (1-(3-nitropyridin-2-yl)piperidin-4-yl)carbamate
Reaction equation
[C:1]([CH3:2])([CH3:3])([CH3:4])[O:5][C:6]([NH:7][CH:8]1[CH2:9][CH2:10][NH:11][CH2:12][CH2:13]1)=[O:14].[CH3:25][N:26]1[CH2:27][CH2:28][CH2:29][C:30]1=[O:31].[Cl:15][c:16]1[n:17][cH:18][cH:19][cH:20][c:21]1[N+:22](=[O:23])[O-:24]>>[C:1]([CH3:2])([CH3:3])([CH3:4])[O:5][C:6]([NH:7][CH:8]1[CH2:9][CH2:10][N:11]([c:16]2[n:17][cH:18][cH:19][cH:20][c:21]2[N+:22](=[O:23])[O-:24])[CH2:12][CH2:13]1)=[O:14]Participants
4
Sources & evidence
- ORD record
- ord-e6e3b2fa8b13453ea1839519397abc10
- Source dataset
- Validation data from https://doi.org/10.1039/C8SC04228D
Reaction notes
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