Acetate → 8-[(2-Chloro-5-fluoropyridin-4-yl)amino]-2-methyl-3,4-dihydroisoquinolin-1-one

HRID 944350

Reaction equation

[C:14](=[O:15])([O-:16])[O-:17].[CH3:20][C:21]1([CH3:22])[c:23]2[cH:24][cH:25][cH:26][c:27]([P:28]([c:29]3[cH:30][cH:31][cH:32][cH:33][cH:34]3)[c:35]3[cH:36][cH:37][cH:38][cH:39][cH:40]3)[c:41]2[O:42][c:43]2[c:44]1[cH:45][cH:46][cH:47][c:48]2[P:49]([c:50]1[cH:51][cH:52][cH:53][cH:54][cH:55]1)[c:56]1[cH:57][cH:58][cH:59][cH:60][cH:61]1.[CH3:86][CH2:87][O:88][CH2:89][CH3:90].[Cl:62][c:63]1[n:64][cH:65][c:66]([F:70])[c:67]([I:69])[cH:68]1.[Cs+:18].[Cs+:19].[NH2:1][c:2]1[cH:3][cH:4][cH:5][c:6]2[c:11]1[C:10](=[O:12])[N:9]([CH3:13])[CH2:8][CH2:7]2.[O-:78][C:79]([CH3:80])=[O:81].[O-:82][C:83]([CH3:84])=[O:85].[O:71]1[CH2:72][CH2:73][O:74][CH2:75][CH2:76]1.[Pd+2:77]>>[NH:1]([c:2]1[cH:3][cH:4][cH:5][c:6]2[c:11]1[C:10](=[O:12])[N:9]([CH3:13])[CH2:8][CH2:7]2)[c:67]1[c:66]([F:70])[cH:65][n:64][c:63]([Cl:62])[cH:68]1